Progressive Labs Niacin 500mg Sustained Release is formulated to release part of the niacin quickly, with the remainder being released over several hours with little or no flushing. Niacin deficiency, known as pellagra, affects every cell, but is most critical in tissues with rapid turnover such as the skin, gastrointestinal tract and nerves.
Niacin reduces the production of LDL and VLDL in the liver and increases the production of beneficial HDL which draws cholesterol away from the lining of the arteries. It removes triglycerides from the blood through a process called “lipoprotein lipase activity” and appears to have a strong effect on the production of prostaglandins. Niacin also dilates the blood vessels which improve circulation and helps flush out existing plaque.
Niacin may produce temporary flushing, tingling, itching, redness and feelings of warmth in some individuals. This effect is normal and usually disappears with continued use.